Zymeworks

Senior Scientist, Oncology

Therapeutic & Translational Research - Vancouver, BC

Description

Zymeworks is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation bispecific and multifunctional biotherapeutics, initially focused on the treatment of cancer. Zymeworks’ suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates.

About the Position

Zymeworks is seeking a highly motivated Senior Scientist to join the Oncology Department to lead a group of researchers evaluating novel therapies in the field of cancer immunotherapy. This individual will explore mechanism of action and therapeutic response to drive the selection of lead therapeutic candidates. This individual will work closely with other disciplines within Zymeworks to lead research stage programs through to IND.

This position will report to the Associate Director, Oncology and will be based in Vancouver, BC.

Key Responsibilities:

• Lead cross-function project teams executing on oncology pipeline projects from inception through to IND.
• Lead small group of researchers primarily supporting antibody-based cancer immunotherapy programs. Develop and assess goals of direct reports.
• Provide in vitro pharmacology expertise to oncology project teams from discovery through to IND.
• Develop innovative in vitro models that enable interrogation of proof-of-concept, mechanisms of action, and mechanisms of resistance.
• Responsible for authoring documents to support regulatory filings and patent applications and manuscripts published in peer-reviewed journals.

Qualifications and Education

• Ph.D. with post-doctoral training or equivalent experience in immunology, oncology, cell biology, or related field is required. A minimum of 5 years of research experience in immunology or related field.
• Demonstrated industry experience with antibody-based bispecific, multi-specific, and drug-conjugate therapeutic modalities.
• Demonstrated experience of in vitro experiments to examine immune cell biology – in particular tumour-immune co-culture assays, T cell activation and survival assays.
• Extensive Flow cytometry experience, including multiparameter, intracellular and phosphoflow.
• Excellent communication and interpersonal skills are required.
• Strong motivation, attention to detail, and ability to think independently and fully integrate into a high achieving team environment.

Why Work for Us?

Innovation. Act with Integrity. Collaboration. Care

We come from many countries, cultures, races, ethnicities, abilities and nationalities. We bring our passions including singing, biking, swimming, dancing, cooking, volunteering, parenting, coaching and much more! We are proud of our nearly equal balance of men and women and strengthened by our non-binary and transgender team members. Every employee belongs.

We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.

How to Apply

NOTE TO EMPLOYMENT AGENCIES: Zymeworks values our relationships with our Recruitment Partners. We will only accept resumes from those partners whom have been contracted by a member of our Human Resources team to collaborate with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.

Zymeworks

Zymeworks is an Equal Opportunity Employer

Submitted: 12/02/2020